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Article

Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome.

Molecular autism - 1 Jan 2017

Ethridge Lauren E, White Stormi P, Mosconi Matthew W, Wang Jun, Pedapati Ernest V, Erickson Craig A, Byerly Matthew J, Sweeney John A

Abstract excerpt

BACKGROUND: Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivities in patients with fragile X syndrome (FXS). The current study investigated functional properties of auditory cortex using a sensory entrainment task in FXS. METHODS: EEG recordings were...

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Share to Acoustic Stimulation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evoked Potentials, Auditory

Share to Fragile X Mental Retardation Protein

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Source

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Identifiers

PMID: 28596820
DOI: 10.1186/s13229-017-0140-1
PMCID: PMC5463459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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