Article
Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome.
Neurobiology of disease - 1 Jul 2018
Lovelace Jonathan W, Ethell Iryna M, Binder Devin K, Razak Khaleel A
Abstract excerpt
Identification of comparable biomarkers in humans and validated animal models will facilitate pre-clinical to clinical therapeutic pipelines to treat neurodevelopmental disorders. Fragile X Syndrome (FXS) is a leading known genetic cause of intellectual disability with symptoms that include increased anxiety, social and sensory processing deficits. Recent EEG studies in humans with FXS have identified neural...
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