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Allele-specific distribution of RNA polymerase II on female X chromosomes.

Human molecular genetics - 15 Oct 2011

Kucera Katerina S, Reddy Timothy E, Pauli Florencia, Gertz Jason, Logan Jenae E, Myers Richard M, Willard Huntington F

Abstract excerpt

While the distribution of RNA polymerase II (PolII) in a variety of complex genomes is correlated with gene expression, the presence of PolII at a gene does not necessarily indicate active expression. Various patterns of PolII binding have been described genome wide; however, whether or not PolII binds at transcriptionally inactive sites remains uncertain. The two X chromosomes in female cells in mammals present...

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Identifiers

PMID: 21791549
DOI: 10.1093/hmg/ddr315
PMCID: PMC3177651

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Source receipt: pubmed, retrieved 7 Sept 2026.

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