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Article

Random X inactivation and extensive mosaicism in human placenta revealed by analysis of allele-specific gene expression along the X chromosome.

PloS one - 4 Jun 2010

Moreira de Mello Joana Carvalho, de Araújo Erica Sara Souza, Stabellini Raquel, Fraga Ana Maria, de Souza Jorge Estefano Santana, Sumita Denilce R, Camargo Anamaria A, Pereira Lygia V

Abstract excerpt

Imprinted inactivation of the paternal X chromosome in marsupials is the primordial mechanism of dosage compensation for X-linked genes between females and males in Therians. In Eutherian mammals, X chromosome inactivation (XCI) evolved into a random process in cells from the embryo proper, where...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20532033
DOI: 10.1371/journal.pone.0010947
PMCID: PMC2881032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20532033-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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