Article
Gene body-specific methylation on the active X chromosome.
Science (New York, N.Y.) - 23 Feb 2007
Hellman Asaf, Chess Andrew
Abstract excerpt
Differential DNA methylation is important for the epigenetic regulation of gene expression. Allele-specific methylation of the inactive X chromosome has been demonstrated at promoter CpG islands, but the overall pattern of methylation on the active X(Xa) and inactive X (Xi) chromosomes is unknown. We performed allele-specific analysis of more than 1000 informative loci along the human X chromosome. The Xa...
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