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Article

Molecular cloning of the human DNA excision repair gene ERCC-6.

Molecular and cellular biology - 1 Nov 1990

Troelstra C, Odijk H, de Wit J, Westerveld A, Thompson L H, Bootsma D, Hoeijmakers J H

Abstract excerpt

The UV-sensitive, nucleotide excision repair-deficient Chinese hamster mutant cell line UV61 was used to identify and clone a correcting human gene, ERCC-6. UV61, belonging to rodent complementation group 6, is only moderately UV sensitive in comparison with mutant lines in groups 1 to 5. It harbors a deficiency in the repair of UV-induced cyclobutane pyrimidine dimers but permits apparently normal repair of...

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Identifiers

PMID: 2172786
DOI: 10.1128/mcb.10.11.5806-5813.1990
PMCID: PMC361360

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Molecular cloning of the human DNA excision repair gene ERCC-6.PMID 2172786Read ↗

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Requirement for ERCC-1 and ERCC-3 gene products in DNA excision repair in vitro. Complementation using rodent and human cell extracts.Semantic proximity Read ↗

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