Article
Localization of the nucleotide excision repair gene ERCC6 to human chromosome 10q11-q21.
Genomics - 1 Apr 1992
Troelstra C, Landsvater R M, Wiegant J, van der Ploeg M, Viel G, Buys C H, Hoeijmakers J H
Abstract excerpt
We have cloned the human DNA excision repair gene ERCC6 by virtue of its ability to correct the uv sensitivity of Chinese hamster overy cell mutant UV61. This mutant is a member of complementation group 6 of the nucleotide excision repair-deficient rodent mutants. By means of in situ hybridizatio...
Topics
- Animals
- CHO Cells
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Cricetinae
- DNA Repair
- Female
- Genetic Linkage
- Humans
- Hybrid Cells
- Male
- Mutation
- Pedigree
- Polymorphism, Restriction Fragment Length
- Restriction Mapping
- Ultraviolet Rays