Requirement for ERCC-1 and ERCC-3 gene products in DNA excision repair in vitro. Complementation using rodent and human cell extracts.

Article

Requirement for ERCC-1 and ERCC-3 gene products in DNA excision repair in vitro. Complementation using rodent and human cell extracts.

The Journal of biological chemistry - 5 Apr 1992

Biggerstaff M, Wood R D

Abstract excerpt

Numerous rodent cell lines exist that have defects in nucleotide excision repair of DNA caused by alterations in genes that fall into 10 different complementation groups. The precise roles in the repair of these genes are unknown. We report here that extracts from Chinese hamster ovary cells of e...

Topics

Animals
CHO Cells
Cell Line
Cricetinae
DNA
DNA Repair
DNA-Binding Proteins
Electrophoresis, Agar Gel
Endonucleases
Genetic Complementation Test
Humans
Mutation
Plasmids
Proteins
Ultraviolet Rays

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