Article
Genetic effect of single-nucleotide polymorphisms in the PPARGC1B gene on airway hyperreactivity in asthmatic patients.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2011
Lee S-H, Jang A-S, Woo Park S, Park J-S, Kim Y K, Uh S-T, Kim Y H, Chung I Y, Park B-L, Shin H D, Park C-S
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1B) is a co-activator for intracellular receptors such as the estrogen receptor, PPAR, and glucocorticoid receptor, which are involved in asthma development. OBJECTIVES: Genetic association of single-nucleotide polymorphisms (SNPs) in the PPARGC1B gene with the risk of asthma and airway hyperreactivity (AHR) was investigated,...
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