Article
G protein-coupled receptor 154 gene polymorphism is associated with airway hyperresponsiveness to methacholine in a Chinese population.
The Journal of allergy and clinical immunology - 1 Mar 2006
Feng Yan, Hong Xiumei, Wang Lin, Jiang Shanqun, Chen Changzhong, Wang Binyan, Yang Jianhua, Fang Zhian, Zang Tonghua, Xu Xiping, Xu Xin
Abstract excerpt
BACKGROUND: A new asthma susceptibility gene, the G protein-coupled receptor for asthma susceptibility (GPRA, GPR154), has recently been identified and the association was replicated in 2 white populations, but not in a Korean population. OBJECTIVE: To test the association between GPR154 gene polymorphisms and airway responsiveness to methacholine in a Chinese population. METHODS: Eight single nucleotide...
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