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Article

PPARG locus haplotype variation and exacerbations in asthma.

Clinical pharmacology and therapeutics - 1 May 2007

Palmer C N A, Doney A S F, Ismail T, Lee S P, Murrie I, Macgregor D F, Mukhopadhyay S

Abstract excerpt

The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates inflammation and may play a role in asthma. Using mouthwash-derived DNA and clinical interviews and measurements, we investigated the association of previously characterized single-nucleotide polymorphisms in the PPARG gene (Pro12Ala, C1431T, and C-681G) with asthma exacerbations in patients aged 3-22 years (n=569). The common homozygous...

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Identifiers

PMID: 17329993
DOI: 10.1038/sj.clpt.6100119

Genes

PPARG

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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