Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.

BMC medical genetics - 20 Oct 2009

Shin Jeong-Ah, Chang Hun Soo, Park Se-Min, Jang An-Soo, Park Sung Woo, Park Jong Sook, Uh Soo-Taek, Il Lim Gune, Rhim Taiyoun, Kim Mi-Kyeong, Choi Inseon S, Chung Il Yup, Park Byung Lae, Shin Hyoung Doo, Park Choon-Sik

Abstract excerpt

BACKGROUND: We previously demonstrated that single nucleotide polymorphism (SNP) and haplotypes were associated with aspirin hypersensitivity in asthmatics. We investigated the genetic effects of the SNPs and haplotypes on the expression of the CysLTR2 gene. METHODS: We measured CysLTR2 protein and mRNA expression in EB virus-infected B cell lines from asthmatics having ht1+/+ and ht2+/+. A gel retardation assay...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Asthma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Hypersensitivity

Share to Electrophoretic Mobility Shift Assay

Share to Flow Cytometry

Share to Gene Expression

Share to Luciferases

Share to RNA Stability

Source

Open in PubMed Open full text

Identifiers

PMID: 19840403
DOI: 10.1186/1471-2350-10-106
PMCID: PMC2770054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.PMID 19840403Read ↗

Association between a polymorphism in cysteinyl leukotriene receptor 2 on chromosome 13q14 and atopic asthma.Semantic proximity Read ↗

Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.Semantic proximity Read ↗

Genetic impact of functional single nucleotide polymorphisms in the 3'-UTR region of the chemoattractant receptor expressed on Th2 cells (CRTH2) gene on asthma and atopy in a Japanese population.Semantic proximity Read ↗

Functional polymorphism and differential regulation of CYSLTR1 transcription in human airway smooth muscle and monocytes.Semantic proximity Read ↗

Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males.Semantic proximity Read ↗

Human CYSLTR1 and GSDML gene polymorphisms detection kit provides a new idea for individualized treatment of asthma and improvement of prognosis.Semantic proximity Read ↗

Polymorphisms in the airway epithelium related genes CDHR3 and EMSY are associated with asthma susceptibilitySemantic proximity Read ↗

Recent advance in investigation of gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

Polymorphisms in the airway epithelium related genes CDHR3 and EMSY are associated with asthma susceptibilitySemantic proximity Read ↗

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association StudiesSemantic proximity Read ↗

Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes.Semantic proximity Read ↗

A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.