Article
Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population.
Carcinogenesis - 1 Feb 2008
Chen Dan, Jin Guangfu, Wang Ying, Wang Haifeng, Liu Hongliang, Liu Yanhong, Fan Weiwei, Ma Hongxia, Miao Ruifeng, Hu Zhibin, Sun Weiwei, Qian Ji, Jin Li, Wei Qingyi, Shen Hongbing, Huang Wei, Lu Daru
Abstract excerpt
Accumulating evidence indicates that activation of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) dampens the inflammation cascade and inhibits tumor growth of the lung, suggesting that it has tumor suppressor functions. We performed a case-control study of 500 incident lung cancer cases and 517 age- and sex frequency-matched cancer-free controls in a Chinese population to investigate the role...
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