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Article

Role of prostanoid DP receptor variants in susceptibility to asthma.

The New England journal of medicine - 21 Oct 2004

Oguma Tsuyoshi, Palmer Lyle J, Birben Esra, Sonna Larry A, Asano Koichiro, Lilly Craig M

Abstract excerpt

BACKGROUND: Previous genetic studies have associated the region of the human genome (14q22.1) containing the gene for the prostanoid DP receptor (PTGDR) with asthma. A study of a mouse model suggests that the receptor is required for the expression of the asthma phenotype. Our associations of asthma with functional genetic variants of PTGDR link these observations. METHODS: We identified and evaluated...

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Source

Identifiers

PMID: 15496624
DOI: 10.1056/NEJMoa031785

Genes

PTGDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of prostanoid DP receptor variants in susceptibility to asthma.PMID 15496624Read ↗

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PTGDR is not a major candidate gene for asthma and atopy in Chinese children.Semantic proximity Read ↗

Relevance and implication of genetic determinants to asthma pathophysiology.Semantic proximity Read ↗

The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases.Semantic proximity Read ↗

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