Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression.

American journal of physiology. Heart and circulatory physiology - 1 Sept 2011

Manichaikul Ani, Wang Qian, Shi Yu Lena, Zhang Zhimin, Leitinger Norbert, Shi Weibin

Abstract excerpt

Ath29 is an atherosclerosis susceptibility locus on chromosome 9 identified in an intercross between C57BL/6 (B6) and C3H/HeJ (C3H) apolipoprotein E-deficient (apoE(-/-)) mice. This locus was subsequently replicated in two separate intercrosses that developed early or advanced atherosclerotic lesions. The objective of this study was to characterize Ath29 through construction and analysis of a congenic strain and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Diseases
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CCL2

Share to Endothelial Cells

Share to Mice, Congenic

Share to Mice, Inbred C3H

Share to Phospholipids

Share to Vascular Cell Adhesion Molecule-1

Source

Open in PubMed Open full text

Identifiers

PMID: 21666121
DOI: 10.1152/ajpheart.00366.2011
PMCID: PMC3191074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression.PMID 21666121Read ↗

Fine Mapping of the Mouse Ath28 Locus Yields Three Atherosclerosis Modifying Sub-Regions.Semantic proximity Read ↗

Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans.Semantic proximity Read ↗

The mouse atherosclerosis locus at chromosome 10 (Ath11) acts early in lesion formation with subcongenic strains delineating 2 narrowed regions.Semantic proximity Read ↗

Genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice.Semantic proximity Read ↗

Fine mapping of Ath6, a quantitative trait locus for atherosclerosis in mice.Semantic proximity Read ↗

Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice.Semantic proximity Read ↗

Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.Semantic proximity Read ↗

Identification of Mep1a as a susceptibility gene for atherosclerosis in mice.Semantic proximity Read ↗

Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation.Semantic proximity Read ↗

Confirmation and high resolution mapping of an atherosclerosis susceptibility gene in mice on Chromosome 1.Semantic proximity Read ↗

Genetic analysis of a mouse cross implicates an anti-inflammatory gene in control of atherosclerosis susceptibility.Semantic proximity Read ↗

Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.