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Article

Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans.

Atherosclerosis - 1 Dec 2004

Korstanje Ron, Eriksson Per, Samnegård Ann, Olsson Per G, Forsman-Semb Kristina, Sen Saunak, Churchill Gary A, Rollins Jarod, Harris Stephen, Hamsten Anders, Paigen Beverly

Abstract excerpt

A previous study revealed that the difference in susceptibility to atherosclerotic lesions between inbred mouse strains SM/J and NZB/BlNJ was determined by one major locus (Ath8). In this study a (SM/J x NZB/BlNJ) F(1) x SM/J backcross localized Ath8 by quantitative trait locus mapping to chromosome 4 with a suggestive LOD score of 2.7. This quantitative trait locus (QTL) was confirmed using an (SM/J x NZB/BlNJ)...

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Source

Identifiers

PMID: 15530921
DOI: 10.1016/j.atherosclerosis.2004.08.006

Genes

ANGPTL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans.PMID 15530921Read ↗

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