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Article

Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2007

Wang Susanna S, Shi Weibin, Wang Xuping, Velky Leandra, Greenlee Sarah, Wang Min T, Drake Thomas A, Lusis Aldons J

Abstract excerpt

OBJECTIVE: C3H/HeJ (C3H) mice are extremely resistant to atherosclerosis. To identify the genetic factors involved in lesion initiation, we studied a cross between C3H and the susceptible strain C57BL/6J (B6) on a hyperlipidemic (apolipoprotein E-null) background. METHODS AND RESULTS: Whereas a previous cross in mice fed a Western diet for 16 weeks revealed a very complex inheritance pattern with many significant...

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Identifiers

PMID: 17916774
DOI: 10.1161/ATVBAHA.107.148106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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