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Article

Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.

PloS one - 1 Jan 2014

Kayashima Yukako, Tomita Hirofumi, Zhilicheva Svetlana, Kim Shinja, Kim Hyung-Suk, Bennett Brian J, Maeda Nobuyo

Abstract excerpt

Apolipoprotein E-null mice on a DBA/2J genetic background (DBA-apoE) are highly susceptible to atherosclerosis in the aortic root area compared with those on a 129S6 background (129-apoE). To explore atherosclerosis-responsible genetic regions, we performed a quantitative trait locus (QTL) analysis using 172 male and 137 female F2 derived from an intercross between DBA-apoE and 129-apoE mice. A genome-wide scan...

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Source

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Identifiers

PMID: 24586312
DOI: 10.1371/journal.pone.0088274
PMCID: PMC3930552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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