Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice.

Atherosclerosis - 1 Nov 2016

Grainger Andrew T, Jones Michael B, Li Jing, Chen Mei-Hua, Manichaikul Ani, Shi Weibin

Abstract excerpt

BACKGROUND AND AIMS: Recent genome-wide association studies (GWAS) have identified over 50 significant loci containing common variants associated with coronary artery disease. However, these variants explain only 26% of the genetic heritability of the disease, suggesting that many more variants remain to be discovered. Here, we examined the genetic basis underlying the marked difference between SM/J-Apoe-/- and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Blood Glucose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 17

Share to Lipids

Share to Lod Score

Share to Major Histocompatibility Complex

Share to Mice, Inbred C3H

Share to Mice, Knockout, ApoE

Source

Open in PubMed Open full text

Identifiers

PMID: 27736672
DOI: 10.1016/j.atherosclerosis.2016.10.011
PMCID: PMC6178236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice.PMID 27736672Read ↗

Genetic analysis of a mouse cross implicates an anti-inflammatory gene in control of atherosclerosis susceptibility.Semantic proximity Read ↗

Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans.Semantic proximity Read ↗

Fine Mapping of the Mouse Ath28 Locus Yields Three Atherosclerosis Modifying Sub-Regions.Semantic proximity Read ↗

Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain.Semantic proximity Read ↗

Identification of Mep1a as a susceptibility gene for atherosclerosis in mice.Semantic proximity Read ↗

Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice.Semantic proximity Read ↗

Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.Semantic proximity Read ↗

Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression.Semantic proximity Read ↗

Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains.Semantic proximity Read ↗

Quantitative trait locus mapping for atherosclerosis susceptibility.Semantic proximity Read ↗

Fine mapping of Ath6, a quantitative trait locus for atherosclerosis in mice.Semantic proximity Read ↗

Genetic-genomic replication to identify candidate mouse atherosclerosis modifier genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.