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Article

Identification of Mep1a as a susceptibility gene for atherosclerosis in mice.

Genetics - 10 Dec 2021

Grainger Andrew T, Pilar Nathanael, Li Jun, Chen Mei-Hua, Abramson Ashley M, Becker-Pauly Christoph, Shi Weibin

Abstract excerpt

Atherosclerosis is the underlying cause of heart attack, ischemic stroke and peripheral arterial disease, and genetic factors involved remain mostly unidentified. We previously identified a significant locus on mouse chromosome 17 for atherosclerosis, Ath49, in an intercross between BALB/c and SM strains. Ath49 partially overlaps in the confidence interval with Ath22 mapped in an AKR × DBA/2 intercross....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34849841
DOI: 10.1093/genetics/iyab160
PMCID: PMC8664597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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