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Article

A somitic Wnt16/Notch pathway specifies haematopoietic stem cells.

Nature - 8 Jun 2011

Clements Wilson K, Kim Albert D, Ong Karen G, Moore John C, Lawson Nathan D, Traver David

Abstract excerpt

Haematopoietic stem cells (HSCs) are a self-renewing population of cells that continuously replenish all blood and immune cells during the lifetime of an individual. HSCs are used clinically to treat a wide array of diseases, including acute leukaemias and congenital blood disorders, but obtaining suitable numbers of cells and finding immune-compatible donors remain serious problems. These difficulties have led...

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Identifiers

PMID: 21654806
DOI: 10.1038/nature10107
PMCID: PMC3304471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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