Article
Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish.
Development (Cambridge, England) - 1 Feb 2002
Liao Eric C, Trede Nikolaus S, Ransom David, Zapata Augustin, Kieran Mark, Zon Leonard I
Abstract excerpt
Vertebrate hematopoiesis occurs in two distinct phases, primitive (embryonic) and definitive (adult). Genes that are required specifically for the definitive program, or for both phases of hematopoiesis, have been described. However, a specific regulator of primitive hematopoiesis has yet to be reported. The zebrafish bloodless (bls) mutation causes absence of embryonic erythrocytes in a dominant but incompletely...
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