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Article

Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling.

Nature - 21 Aug 2014

Kobayashi Isao, Kobayashi-Sun Jingjing, Kim Albert D, Pouget Claire, Fujita Naonobu, Suda Toshio, Traver David

Abstract excerpt

Notch signalling plays a key role in the generation of haematopoietic stem cells (HSCs) during vertebrate development and requires intimate contact between signal-emitting and signal-receiving cells, although little is known regarding when, where and how these intercellular events occur. We previously reported that the somitic Notch ligands, Dlc and Dld, are essential for HSC specification. It has remained...

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Identifiers

PMID: 25119047
DOI: 10.1038/nature13623
PMCID: PMC4237229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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