Article
Drosophila: a model for studying genetic and molecular aspects of haematopoiesis and associated leukaemias
14 Jun 2011
Abstract excerpt
Vertebrate haematopoietic stem cells (HSCs) give rise to a hierarchically organised set of progenitors for erythroid, myeloid, lymphoid and megakaryocyte lineages, and are responsible for lifelong maintenance of the blood system. Dysregulation of the haematopoietic differentiation programme is at the origin of numerous pathologies, including leukaemias. With the discoveries that many transcriptional regulators...
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