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Article

BMP4: Its Role in Development of the Hematopoietic System and Potential as a Hematopoietic Growth Factor

1 Jul 2004

Abstract excerpt

Blood formation occurs throughout the life of an individual in a process driven by hematopoietic stem cells (HSCs). The ability of bone marrow (BM) and cord blood (CB) HSC to undergo self-renewal and develop into multiple blood lineages has made these cells an important clinical resource. Transplantation with BM- and CB-derived HSCs is now used extensively for treatment of hematological disorders, malignancies,...

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PMID: 15277693
DOI: 10.1634/stemcells.22-4-457

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