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Article

Pdgf signalling guides neural crest contribution to the haematopoietic stem cell specification niche.

Nature cell biology - 1 May 2017

Damm Erich W, Clements Wilson K

Abstract excerpt

Haematopoietic stem cells (HSCs) support maintenance of the haematopoietic and immune systems throughout the life of vertebrates, and are the therapeutic component of bone marrow transplants. Understanding native specification of HSCs, to uncover key signals that might help improve in vitro directed differentiation protocols, has been a long-standing biomedical goal. The current impossibility of specifying true...

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Identifiers

PMID: 28394883
DOI: 10.1038/ncb3508
PMCID: PMC5546139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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