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Article

The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study.

The journal of physical chemistry. B - 30 Jun 2011

Wolfson Mikhail Y, Nam Kwangho, Chakraborty Arup K

Abstract excerpt

T cells orchestrate adaptive, pathogen-specific immune responses. T cells have a surface receptor (called TCR) whose ligands are complexes (pMHCs) of peptides (derived from pathogens or host proteins) and major histocompatibility complex proteins (MHCs). MHC proteins vary between hosts. During organ transplants, host TCRs interact with peptides present in complex with genetically different MHCs. This usually...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell

Source

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Identifiers

PMID: 21651302
DOI: 10.1021/jp202471d
PMCID: PMC3131071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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