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Article

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.

Science (New York, N.Y.) - 20 Feb 1998

Garcia K C, Degano M, Pease L R, Huang M, Peterson P A, Teyton L, Wilson I A

Abstract excerpt

The T cell receptor (TCR) inherently has dual specificity. T cells must recognize self-antigens in the thymus during maturation and then discriminate between foreign pathogens in the periphery. A molecular basis for this cross-reactivity is elucidated by the crystal structure of the alloreactive...

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Identifiers

PMID: 9469799
DOI: 10.1126/science.279.5354.1166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9469799-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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