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Article

Transmission distortion in Crohn's disease risk gene ATG16L1 leads to sex difference in disease association.

Inflammatory bowel diseases - 1 Feb 2012

Liu Linda Y, Schaub Marc A, Sirota Marina, Butte Atul J

Abstract excerpt

BACKGROUND: Crohn's disease (CD), an inflammatory disease of the bowel, affects millions of people around the world. Evidence suggests that disease onset and pathogenesis differ between males and females. Yet no comprehensive efforts exist to assess the sex-specific genetic architecture of CD. METHODS: We used genotyping data from a cohort of 1748 CD cases and 2938 controls to investigate 71...

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PMID: 21618365
DOI: 10.1002/ibd.21781
PMCID: PMC3165065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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