Article
ATG16L1 and IL23R variants and genetic susceptibility to crohn's disease: mode of inheritance based on meta-analysis of genetic association studies.
Inflammatory bowel diseases - 1 Apr 2015
Grigoras Christos A, Ziakas Panayiotis D, Jayamani Elamparithi, Mylonakis Eleftherios
Abstract excerpt
BACKGROUND: Autophagy and regulation of IL-23 signaling pathways have been implicated in the pathogenesis of Crohn's disease (CD). We studied the mode of inheritance and reviewed the association of 2 polymorphic variants of ATG16L1 and IL23R with CD. METHODS: We searched the PubMed and ISI Web of Science databases (up to May 2014) for pertinent articles. We included all studies that had a case-control design,...
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