Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.

doi:10.1002/ibd.20162

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Article

Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.

Inflammatory bowel diseases - 1 Aug 2007

Cummings J R Fraser, Cooney Rachel, Pathan Saad, Anderson Carl A, Barrett Jeffrey C, Beckly John, Geremia Alessandra, Hancock Laura, Guo Changcun, Ahmad Tariq, Cardon Lon R, Jewell Derek P

Abstract excerpt

BACKGROUND: A German genome-wide nonsynonymous single nucleotide polymorphism (nsSNP) association study identified ATG16L1 as a Crohn's disease (CD) susceptibility gene. The association appeared to be confined to the nsSNP rs2,241,880 and was confirmed in 2 German independent case-control collections (combined P = 4.0 x 10(-8), odds ratio [OR] 1.45; 95% confidence interval [CI]: 1.21-1.74), a CD transmission...

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PMID: 17455206
DOI: 10.1002/ibd.20162

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Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.PMID 17455206Read ↗

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