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Article

Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene.

Expert review of molecular diagnostics - 1 Mar 2008

Grant Struan F A, Baldassano Robert N, Hakonarson Hakon

Abstract excerpt

Inflammatory bowel disease constitutes two related clinical entities, Crohn's disease (CD) and ulcerative colitis (UC), both of which have increased in prevalence over the last decade. Family and twin studies have strongly indicated that genetic factors play a large role in an individual's risk of developing inflammatory bowel disease. Despite this, it has proven difficult to isolate disease genes that confer...

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PMID: 18366306
DOI: 10.1586/14737159.8.2.199

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