Article

Sex differences in disease genetics

2016-07-13

Abstract excerpt

There is long-standing evidence for gene-by-sex interactions in disease risk, which can now be tested in genome-wide association studies with participant numbers in the hundreds of thousands. Contemporary methods start with a separate test for each sex, but simulations suggest a more powerful approach should be to use sex as an interaction term in a single test. The traits currently with the most compelling eviden...

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Literature Corpus work: f2194eb0-e0a0-534b-83b2-7941835f5e9c
DOI: 10.1101/063651

Open publication

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