Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.

doi:10.1136/gutjnl-2013-305193

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Article

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.

Gut - 1 Jan 2014

Yang Suk-Kyun, Hong Myunghee, Zhao Wanting, Jung Yusun, Baek Jiwon, Tayebi Naeimeh, Kim Kyung Mo, Ye Byong Duk, Kim Kyung-Jo, Park Sang Hyoung, Lee Inchul, Lee Eun-Ju, Kim Won Ho, Cheon Jae Hee, Kim Young-Ho, Jang Byung Ik, Kim Hyun-Soo, Choi Jai Hyun, Koo Ja Seol, Lee Ji Hyun, Jung Sung-Ae, Lee Yeoun Joo, Jang Joo Young, Shin Hyoung Doo, Kang Daehee, Youn Hee-Shang, Liu Jianjun, Song Kyuyoung

Abstract excerpt

OBJECTIVE: Crohn's disease (CD) is an intractable inflammatory bowel disease (IBD) of unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and Immunochip data identified 163 susceptibility loci to IBD in Caucasians, however there are limited studies in other populations. METHODS: We performed a GWAS and two validation studies in the Korean population comprising a total of 2311...

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PMID: 23850713
DOI: 10.1136/gutjnl-2013-305193

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