Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SIRT3 and cancer: Tumor promoter or suppressor?

10 May 2011

Abstract excerpt

Sirtuins (SIRT1-7), the mammalian homologues of the Sir2 gene in yeast, have emerging roles in age-related diseases, such as cardiac hypertrophy, diabetes, obesity, and cancer. However, the role of several sirtuin family members, including SIRT1 and SIRT3, in cancer has been controversial. The aim of this review is to explore and discuss the seemingly dichotomous role of SIRT3 in cancer biology with particular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Calcium signaling and nucleotide metabolism
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21586315
DOI: 10.1016/j.bbcan.2011.04.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SIRT3 and cancer: Tumor promoter or suppressor?PMID 21586315Read ↗

Sirtuin-3 (SIRT3) and the Hallmarks of CancerSemantic proximity Read ↗

The Roles of SIRT1 in CancerSemantic proximity Read ↗

Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancerSemantic proximity Read ↗

Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant PhenotypeSemantic proximity Read ↗

Sirtuin 3: A Janus face in cancer (Review)Semantic proximity Read ↗

Emerging role of sirtuins on tumorigenesis: possible link between aging and cancerSemantic proximity Read ↗

SIRT3: Oncogene and Tumor Suppressor in CancerSemantic proximity Read ↗

The Roles of Sirtuin Family Proteins in Cancer ProgressionSemantic proximity Read ↗

SIRT1: a potential tumour biomarker and therapeutic targetSemantic proximity Read ↗

Function of the SIRT 3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative diseaseSemantic proximity Read ↗

Rejuvenating Sirtuins: The Rise of a New Family of Cancer Drug TargetsSemantic proximity Read ↗

SIRT6Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.