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Article

Function of the SIRT 3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease

29 Sept 2016

Abstract excerpt

In mammals, seven members of the sirtuin protein family known as class III histone deacetylase have been identified for their characteristic features. These distinguished characteristics include the tissues where they are distributed or located, enzymatic activities, molecular functions, and involvement in diseases. Among the sirtuin members, SIRT3 has received much attention for its role in cancer genetics,...

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PMID: 27686535
DOI: 10.1111/acel.12538

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