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Article

SIRT1: a potential tumour biomarker and therapeutic target

6 May 2019

Abstract excerpt

SIRT1, which is highly homologous to yeast silent information regulator 2, has recently garnered tremendous attention because of its various regulatory effects in several pathological conditions. Numerous studies have found that SIRT1 is highly expressed in a broad range of tumours compared with the paracancerous tissue. However, the role of SIRT1 in malignancies has yet to be systematically elucidated, and its...

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PMID: 31056963
DOI: 10.1080/1061186x.2019.1605519

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