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SAMP1/YitFc mouse strain: A spontaneous model of Crohnʼs disease-like ileitis

6 May 2011

Abstract excerpt

The SAMP1/YitFc mouse strain represents a model of Crohn's disease (CD)-like ileitis that is ideal for investigating the pathogenesis of chronic intestinal inflammation. Different from the vast majority of animal models of colitis, the ileal-specific phenotype characteristic of SAMP1/YitFc mice occurs spontaneously, without genetic, chemical, or immunological manipulation. In addition, SAMP1/YitFc mice possess...

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PMID: 21557393
DOI: 10.1002/ibd.21638

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