Article
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis.
Gastroenterology - 1 Apr 2003
Rivera-Nieves Jesús, Bamias Giorgos, Vidrich Alda, Marini Marco, Pizarro Theresa T, McDuffie Marcia J, Moskaluk Christopher A, Cohn Steven M, Cominelli Fabio
Abstract excerpt
BACKGROUND & AIMS: SAMP1/Yit mice spontaneously develop chronic terminal ileitis, reminiscent of the human disease described by Crohn et al. in 1932. Several new phenotypic features have appeared in our colony after more than 20 generations of brother-sister mating. In this report, we describe the distinguishing features of the SAMP1/YitFc substrain at the University of Virginia, compared with the Japanese...
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