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Article

Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization.

PloS one - 22 Apr 2011

Hawthorn Lesleyann, Cowell John K

Abstract excerpt

Wilms tumor (WT) has been a model to study kidney embryogenesis and tumorigenesis and, although associated with hereditary, cancer predisposition syndromes, the majority of tumors occur sporadically. To analyze genetic changes in WT we have defined copy number changes and loss of heterozygosity in 56 Wilms tumors using high resolution oligonucleotide arrays at a average resolution of ~12 Kb. Consistent deletions...

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Identifiers

PMID: 21544195
DOI: 10.1371/journal.pone.0018941
PMCID: PMC3081321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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