Article
SNP-based arrays complement classic cytogenetics in the detection of chromosomal aberrations in Wilms' tumor.
Cancer genetics - 1 Mar 2012
Zin Reena, Pham Kym, Ashleigh Murch, Ravine David, Waring Paul, Charles Adrian
Abstract excerpt
Wilms' tumors have characteristic chromosomal abnormalities, such as the 11p13 deletion, in a subset of cases. This is one of the very few reports comparing single nucleotide polymorphism (SNP) array analysis with conventional karyotyping of Wilms' tumors. A total of 43 frozen tumor samples were analyzed using the Affymetrix Cytogenetics Whole-Genome 2.7M array. The findings from the SNP array analysis were then...
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