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Article

Array CGH Analysis of Paired Blood and Tumor Samples from Patients with Sporadic Wilms Tumor.

PloS one - 1 Jan 2015

Cabral de Almeida Cardoso Leila, Rodriguez-Laguna Lara, Del Carmen Crespo María, Vallespín Elena, Palomares-Bralo María, Martin-Arenas Rubén, Rueda-Arenas Inmaculada, Silvestre de Faria Paulo Antonio, García-Miguel Purificación, Lapunzina Pablo, Regla Vargas Fernando, Seuanez Hector N, Martínez-Glez Víctor

Abstract excerpt

Wilms tumor (WT), the most common cancer of the kidney in infants and children, has a complex etiology that is still poorly understood. Identification of genomic copy number variants (CNV) in tumor genomes provides a better understanding of cancer development which may be useful for diagnosis and therapeutic targets. In paired blood and tumor DNA samples from 14 patients with sporadic WT, analyzed by aCGH, 22% of...

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Identifiers

PMID: 26317783
DOI: 10.1371/journal.pone.0136812
PMCID: PMC4552764

Genes

BMP2
CTNNB1
NEK1
PIAS4
SALL4
SIX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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