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Article

Southern-blot analyses of human T-lymphocyte mutants induced in vitro by gamma-irradiation.

Mutation research - 1 Feb 1990

O'Neill J P, Hunter T C, Sullivan L M, Nicklas J A, Albertini R J

Abstract excerpt

G0 phase cultures of human peripheral blood T-lymphocytes from a single individual were exposed to 300 rad of gamma-irradiation from a 137Cs source and cultured in vitro for 8 days to allow phenotypic expression. Thioguanine-resistant (TGr) mutants were isolated by a cell cloning assay in microtiter plates. These mutants were studied by Southern blot analysis to define the gross structural alterations in the...

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Source

Identifiers

PMID: 2153929
DOI: 10.1016/0165-1218(90)90018-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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