Ionizing radiation signature mutations in human cell mutants induced by low-dose exposures.

doi:10.1093/mutage/11.3.275

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Ionizing radiation signature mutations in human cell mutants induced by low-dose exposures.

Mutagenesis - 1 May 1996

Nelson S L, Parks K K, Grosovsky A J

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Investigation of mutational specificity at low doses has generally not been possible since the number of induced mutants may be similar or significantly lower than the spontaneous background. The use of a low-dose fractionated exposure protocol in TK6 human lymphoblasts results in an incremental accumulation of mutants induced by individual 20 cGy gamma-ray exposures. Therefore, the frequency of induced mutants...

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Ionizing radiation signature mutations in human cell mutants induced by low-dose exposures.

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Ionizing radiation signature mutations in human cell mutants induced by low-dose exposures.

Abstract excerpt

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