Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy.

doi:10.1016/j.seizure.2011.04.003

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Article

Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy.

Seizure - 1 Sept 2011

Haerian B S, Lim K S, Mohamed E H M, Tan H J, Tan C T, Raymond A A, Wong C P, Wong S W, Mohamed Z

Abstract excerpt

Approximately one third of newly treated epilepsy patients do not respond to antiepileptic drugs (AEDs). Overexpression of P-glycoprotein (P-gp) efflux transporter has been proposed to have a critical role in causing resistance to AEDs. P-gp is a product of the ATP-binding cassette subfamily B member 1 (ABCB1) gene. The purpose of this study was to investigate a possible link between ABCB1 rs3789243 C>T, C1236T,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21530324
DOI: 10.1016/j.seizure.2011.04.003

Genes

ABCB1

Variants

rs3789243
rs3789243
rs3789243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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