Lack of association between ABCC2 gene variants and treatment response in epilepsy.

doi:10.2217/pgs.11.143

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Lack of association between ABCC2 gene variants and treatment response in epilepsy.

Pharmacogenomics - 1 Jan 2012

Hilger Eva, Reinthaler Eva Maria, Stogmann Elisabeth, Hotzy Christoph, Pataraia Ekaterina, Baumgartner Christoph, Zimprich Alexander, Zimprich Fritz

Abstract excerpt

AIM: The aim of this study was to replicate a previously reported association between drug resistance in epilepsy patients and the 24C>T variant of the ABCC2 gene that codes for the drug efflux transporter MRP2. PATIENTS & METHODS: We genotyped 381 Caucasian epileptic patients (337 drug resistant and 44 drug responsive) and 247 healthy controls for the ABCC2 gene -24C>T polymorphism (rs717620) and two other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Pharmacological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epilepsy

Share to Genetic Association Studies

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Multidrug Resistance-Associated Protein 2

Share to Multidrug Resistance-Associated Proteins

Share to Seizures

Source

Open in PubMed

Identifiers

PMID: 22256867
DOI: 10.2217/pgs.11.143

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between ABCC2 gene variants and treatment response in epilepsy.PMID 22256867Read ↗

Lack of association between polymorphism in ABCC2 gene and response to antiepileptic drug treatment in Croatian patients with epilepsy.Semantic proximity Read ↗

The ABCC2 c.-24C>T polymorphism increases the risk of resistance to antiepileptic drugs: A meta-analysis.Semantic proximity Read ↗

A systematic review and meta-analysis of the role of ABCC2 variants on drug response in patients with epilepsy.Semantic proximity Read ↗

Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy.Semantic proximity Read ↗

ABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients.Semantic proximity Read ↗

Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy.Semantic proximity Read ↗

No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population.Semantic proximity Read ↗

ABCC2 rs2273697, rs717620, rs3740066 Polymorphisms and Antiseizure Medication Resistance: A Systematic Review and Meta-AnalysisSemantic proximity Read ↗

Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy.Semantic proximity Read ↗

The effects of ABCC2 G1249A polymorphism on the risk of resistance to antiepileptic drugs: a meta-analysis of the literature.Semantic proximity Read ↗

A systematic review and meta-analysis of the association of ABCC2/ABCG2 polymorphisms with antiepileptic drug responses in epileptic patients.Semantic proximity Read ↗

Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.