Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of ABCB1 gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis.

Pharmacogenomics - 1 May 2011

Haerian Batoul Sadat, Lim Kheng Seang, Tan Chong Tin, Raymond Azman Ali, Mohamed Zahurin

Abstract excerpt

AIMS: Several studies demonstrated a link between ABCB1 gene variants and the response to treatment in epilepsy, but the results have been inconclusive. Here, we performed the first haplotype meta-analysis to examine the association of haplotypes of ABCB1 common variants with the response to treatment in epilepsy. MATERIALS & METHODS: We meta-analyzed the studies that evaluated the role of ABCB1 C1236T, G2677T/A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Epilepsy

Share to Genome-Wide Association Study

Share to Haplotypes

Share to Polymorphism, Genetic

Share to Treatment Outcome

Source

Identifiers

PMID: 21391884
DOI: 10.2217/pgs.10.212

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of ABCB1 gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis.PMID 21391884Read ↗

Association between ABCB1 polymorphisms and response to antiepileptic drugs among Jordanian epileptic patients.Semantic proximity Read ↗

The roles of variants in human multidrug resistance (MDR1) gene and their haplotypes on antiepileptic drugs response: a meta-analysis of 57 studies.Semantic proximity Read ↗

Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy.Semantic proximity Read ↗

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.Semantic proximity Read ↗

Polymorphisms in the Drug Transporter Gene ABCB1 Are Associated with Drug Response in Saudi Epileptic Pediatric PatientsSemantic proximity Read ↗

Association between ABCB1 polymorphisms and response to first-generation antiepileptic drugs in a Tunisian epileptic population.Semantic proximity Read ↗

Association between G2677T/A polymorphism in ABCB1 gene and the risk of drug resistance epilepsy: An updated systematic review and meta-analysis.Semantic proximity Read ↗

A systematic review and meta-analysis of the association of ABCC2/ABCG2 polymorphisms with antiepileptic drug responses in epileptic patients.Semantic proximity Read ↗

Polymorphisms Affecting the Response to Novel Antiepileptic Drugs.Semantic proximity Read ↗

Polymorphism in drug transporter gene ABCB1 is associated with drug resistance in Pakistani epilepsy patients.Semantic proximity Read ↗

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.Semantic proximity Read ↗

Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.