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Article

Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.

Biochimie - 1 Sept 2010

Grover Sandeep, Bala Kiran, Sharma Sangeeta, Gourie-Devi M, Baghel Ruchi, Kaur Harpreet, Gupta Meenal, Talwar Puneet, Kukreti Ritushree

Abstract excerpt

Over-expression of efflux transporter P-glycoprotein (PgP) encoded by ABCB1 gene has been implicated in poor responsive epilepsy. Several genetic variants have been shown to influence the expression levels of P-glycoprotein. The aim of the present study was to investigate the role of ABCB1 polymorphisms: C1236T, G2677T/A and C3435T in determining drug response to first line antiepileptic drugs (AEDs) namely...

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Source

Identifiers

PMID: 20417680
DOI: 10.1016/j.biochi.2010.04.008

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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