Article
No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population.
Epilepsy & behavior : E&B - 1 Jan 2009
Lakhan R, Misra U K, Kalita J, Pradhan S, Gogtay N J, Singh M K, Mittal B
Abstract excerpt
Multiple drug resistance is a common problem in the treatment of epilepsy, and approximately 30% of patients continue to have seizures despite all therapeutic interventions. Among various classes of drug transporters, genetic variants of P-glycoprotein (P-gp) encoded by the ABCB1 (ATP-binding cassette subfamily B member 1) gene have been associated with drug-refractory epilepsy. Our aim was to investigate the...
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