Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of an insertion in the 5'UTR of the AMCase on gene expression and pulmonary functions.

Respiratory medicine - 1 Aug 2011

Birben Esra, Sackesen Cansın, Kazani Shamsah, Tincer Gizem, Karaaslan Cagatay, Durgunsu Berna, Gürsel Ihsan, Wechsler Michael E, Israel Elliot, Kalayci Omer

Abstract excerpt

BACKGROUND: Studies regarding the physiological role of acidic mammalian chitinase (AMCase) and the effects of its genetic variants on asthma have produced conflicting results. OBJECTIVES: We aimed to determine the genetic variants in the AMCase gene that could regulate the gene expression and thus influence disease severity. METHODS: Genetic variants of the AMCase gene were determined by sequencing of asthmatics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Enzyme-Linked Immunosorbent Assay
Share to 5' Untranslated Regions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age Factors

Share to Asthma

Share to Chitinases

Share to Forced Expiratory Volume

Share to Mutagenesis, Insertional

Share to Turkey

Source

Identifiers

PMID: 21511453
DOI: 10.1016/j.rmed.2011.03.017

Genes

FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of an insertion in the 5'UTR of the AMCase on gene expression and pulmonary functions.PMID 21511453Read ↗

Polymorphisms and Haplotypes of Acid Mammalian Chitinase Are Associated with Bronchial AsthmaSemantic proximity Read ↗

Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels.Semantic proximity Read ↗

Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs.Semantic proximity Read ↗

Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit.Semantic proximity Read ↗

Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein.Semantic proximity Read ↗

The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.Semantic proximity Read ↗

Joint influences of Acidic-Mammalian-Chitinase with Interleukin-4 and Toll-like receptor-10 with Interleukin-13 in the genetics of asthma.Semantic proximity Read ↗

Association between risk of asthma and gene polymorphisms in CHI3L1 and CHIA: a systematic meta-analysis.Semantic proximity Read ↗

Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.Semantic proximity Read ↗

Interaction Between Catalase Gene Promoter Polymorphisms and Indoor Environmental Exposure in Childhood Allergic Rhinitis.Semantic proximity Read ↗

Genetic association between human chitinases and lung function in COPD.Semantic proximity Read ↗

Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.